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Rama Rao Amara Selected Research

Vaccinia

1/2022A modified vaccinia Ankara vaccine expressing spike and nucleocapsid protects rhesus macaques against SARS-CoV-2 Delta infection.
9/2021PD-1 blockade and vaccination provide therapeutic benefit against SIV by inducing broad and functional CD8+ T cells in lymphoid tissue.
1/2021A modified vaccinia Ankara vector-based vaccine protects macaques from SARS-CoV-2 infection, immune pathology, and dysfunction in the lungs.
11/2019Strong TH1-biased CD4 T cell responses are associated with diminished SIV vaccine efficacy.
1/2019HIV-1 vaccination by needle-free oral injection induces strong mucosal immunity and protects against SHIV challenge.
1/2018A Trimeric HIV-1 Envelope gp120 Immunogen Induces Potent and Broad Anti-V1V2 Loop Antibodies against HIV-1 in Rabbits and Rhesus Macaques.
10/2017Immunogenicity and efficacy of DNA/MVA HIV vaccines in rhesus macaque models.
11/2016High Doses of GM-CSF Inhibit Antibody Responses in Rectal Secretions and Diminish Modified Vaccinia Ankara/Simian Immunodeficiency Virus Vaccine Protection in TRIM5α-Restrictive Macaques.
1/2016Strong, but Age-Dependent, Protection Elicited by a Deoxyribonucleic Acid/Modified Vaccinia Ankara Simian Immunodeficiency Virus Vaccine.
2/2012SIVmac239 MVA vaccine with and without a DNA prime, similar prevention of infection by a repeated dose SIVsmE660 challenge despite different immune responses.
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Rama Rao Amara Research Topics

Disease

30Infections
11/2021 - 10/2002
22Vaccinia
01/2022 - 05/2002
10Acquired Immunodeficiency Syndrome (AIDS)
10/2019 - 05/2002
6Viremia
09/2021 - 03/2005
6HIV Infections (HIV Infection)
10/2019 - 10/2003
4Communicable Diseases (Infectious Diseases)
09/2014 - 04/2005
4Tuberculosis (Tuberculoses)
01/2014 - 04/2003
4Virus Diseases (Viral Diseases)
02/2010 - 08/2002
3Disease Progression
10/2017 - 03/2009
2COVID-19
11/2021 - 01/2021
2Smallpox (Variola)
09/2007 - 04/2004
1Hepatitis D
01/2022
1Inflammation (Inflammations)
01/2021
1Dyskinesias (Dyskinesia)
11/2020
1Parkinson Disease (Parkinson's Disease)
11/2020
1Hypergammaglobulinemia (Hyperimmunoglobulinemia)
01/2016
1Breakthrough Infections
08/2015
1Human Influenza (Influenza)
01/2011
1Bacterial Infections (Bacterial Infection)
01/2011
1Mpox (monkeypox)
09/2007
1Persistent Infection
08/2007
1Pulmonary Tuberculosis
04/2003

Drug/Important Bio-Agent (IBA)

30VaccinesIBA
01/2022 - 08/2002
20DNA (Deoxyribonucleic Acid)IBA
09/2021 - 05/2002
9Proteins (Proteins, Gene)FDA Link
11/2021 - 04/2003
5Neutralizing AntibodiesIBA
11/2021 - 09/2007
5AntigensIBA
09/2021 - 10/2003
5AntibodiesIBA
01/2019 - 05/2009
5MVA vaccineIBA
02/2012 - 05/2002
5A-Form DNA (A-DNA)IBA
02/2012 - 04/2007
5Antiviral Agents (Antivirals)IBA
02/2010 - 10/2002
4Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA
11/2016 - 09/2006
4AIDS VaccinesIBA
10/2016 - 09/2007
4SAIDS VaccinesIBA
04/2015 - 12/2010
4EpitopesIBA
01/2011 - 10/2003
3Immunoglobulin G (IgG)IBA
01/2019 - 01/2016
3CytokinesIBA
01/2019 - 04/2004
3Immunoglobulin A (IgA)IBA
11/2016 - 02/2012
2CD40 Ligand (CD40L)IBA
09/2021 - 09/2014
2InterferonsIBA
01/2021 - 11/2019
2Broadly Neutralizing AntibodiesIBA
01/2018 - 01/2011
2Recombinant DNA (Recombinant DNA Research)IBA
02/2012 - 07/2011
2Smallpox Vaccine (Vaccine, Smallpox)FDA Link
09/2007 - 08/2007
1FurinIBA
01/2022
1aluminum sulfate (alum)IBA
11/2021
1Granzymes (Granzyme)IBA
09/2021
1RNA (Ribonucleic Acid)IBA
01/2021
1Transforming Growth Factor beta (TGF-beta)IBA
11/2020
1Levodopa (L Dopa)FDA LinkGeneric
11/2020
1GP 140IBA
10/2019
1Peptides (Polypeptides)IBA
10/2019
1Interleukin-12 (IL 12)IBA
01/2019
1Viral RNAIBA
01/2019
1Interleukin-18 (Interleukin 18)IBA
01/2019
1FlagellinIBA
01/2019
1Interleukin-7 (Interleukin 7)IBA
01/2019
1antineoplaston A10 (A 10)IBA
01/2016
1Glycoproteins (Glycoprotein)IBA
01/2013
1Subunit VaccinesIBA
01/2013
1Monoclonal AntibodiesIBA
01/2011
1Hemagglutinins (Hemagglutinin)IBA
01/2011
1Interleukin-17 (Interleukin 17)IBA
01/2011
1Recombinant ProteinsIBA
01/2011
1LigandsIBA
06/2007
1Immune Sera (Antisera)IBA
09/2006
1EnzymesIBA
05/2005
1Interleukin-2 (IL2)IBA
03/2005
1Interferon-gamma (Interferon, gamma)IBA
04/2003
1Tuberculin (PPD)IBA
04/2003
1Mycobacterium tuberculosis antigensIBA
04/2003
1Viral DNAIBA
10/2002

Therapy/Procedure

2Therapeutics
11/2020 - 03/2009
2Highly Active Antiretroviral Therapy (HAART)
03/2006 - 10/2002
1Art Therapy
08/2015
1Euthanasia (Mercy Killing)
03/2005